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BNTA alleviates inflammatory osteolysis by the SOD mediated anti-oxidation and anti-inflammation effect on inhibiting osteoclastogenesis

Abnormal activation and overproliferation of osteoclast in inflammatory bone diseases lead to osteolysis and bone mass loss. Although current pharmacological treatments have made extensive advances, limitations still exist. N-[2-bromo-4-(phenylsulfonyl)-3-thienyl]-2-chlorobenzamide (BNTA) is an arti...

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Detalles Bibliográficos
Autores principales: Wang, Huidong, Cao, Xiankun, Guo, Jiadong, Yang, Xiao, Sun, Xiaojiang, Fu, Zhiyi, Qin, An, Wu, Yujie, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559729/
https://www.ncbi.nlm.nih.gov/pubmed/36249770
http://dx.doi.org/10.3389/fphar.2022.939929