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Micronuclei from misaligned chromosomes that satisfy the spindle assembly checkpoint in cancer cells
Chromosome alignment to the spindle equator is a hallmark of mitosis thought to promote chromosome segregation fidelity in metazoans. Yet chromosome alignment is only indirectly supervised by the spindle assembly checkpoint (SAC) as a byproduct of chromosome bi-orientation, and the consequences of d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559752/ https://www.ncbi.nlm.nih.gov/pubmed/36057259 http://dx.doi.org/10.1016/j.cub.2022.08.026 |