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Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using (111)In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements

Progressive loss of β-cell mass (BCM) has a pernicious influence on type 2 diabetes mellitus (T2DM); evaluation of BCM has conventionally required an invasive method that provides only cross-sectional data. However, a noninvasive approach to longitudinal assessment of BCM in living subjects using an...

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Detalles Bibliográficos
Autores principales: Fauzi, Muhammad, Murakami, Takaaki, Fujimoto, Hiroyuki, Botagarova, Ainur, Sakaki, Kentaro, Kiyobayashi, Sakura, Ogura, Masahito, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559817/
https://www.ncbi.nlm.nih.gov/pubmed/36246910
http://dx.doi.org/10.3389/fendo.2022.1010825