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Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using (111)In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements
Progressive loss of β-cell mass (BCM) has a pernicious influence on type 2 diabetes mellitus (T2DM); evaluation of BCM has conventionally required an invasive method that provides only cross-sectional data. However, a noninvasive approach to longitudinal assessment of BCM in living subjects using an...
Autores principales: | Fauzi, Muhammad, Murakami, Takaaki, Fujimoto, Hiroyuki, Botagarova, Ainur, Sakaki, Kentaro, Kiyobayashi, Sakura, Ogura, Masahito, Inagaki, Nobuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559817/ https://www.ncbi.nlm.nih.gov/pubmed/36246910 http://dx.doi.org/10.3389/fendo.2022.1010825 |
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