Resurrecting essential amino acid biosynthesis in mammalian cells

Major genomic deletions in independent eukaryotic lineages have led to repeated ancestral loss of biosynthesis pathways for nine of the twenty canonical amino acids. While the evolutionary forces driving these polyphyletic deletion events are not well understood, the consequence is that extant metaz...

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Detalles Bibliográficos
Autores principales: Trolle, Julie, McBee, Ross M, Kaufman, Andrew, Pinglay, Sudarshan, Berger, Henri, German, Sergei, Liu, Liyuan, Shen, Michael J, Guo, Xinyi, Martin, J Andrew, Pacold, Michael E, Jones, Drew R, Boeke, Jef D, Wang, Harris H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560156/
https://www.ncbi.nlm.nih.gov/pubmed/36165439
http://dx.doi.org/10.7554/eLife.72847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560156/
https://www.ncbi.nlm.nih.gov/pubmed/36165439
http://dx.doi.org/10.7554/eLife.72847

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