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Robust cone-mediated signaling persists late into rod photoreceptor degeneration

Rod photoreceptor degeneration causes deterioration in the morphology and physiology of cone photoreceptors along with changes in retinal circuits. These changes could diminish visual signaling at cone-mediated light levels, thereby limiting the efficacy of treatments such as gene therapy for rescui...

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Detalles Bibliográficos
Autores principales: Scalabrino, Miranda L, Thapa, Mishek, Chew, Lindsey A, Zhang, Esther, Xu, Jason, Sampath, Alapakkam P, Chen, Jeannie, Field, Greg D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560159/
https://www.ncbi.nlm.nih.gov/pubmed/36040015
http://dx.doi.org/10.7554/eLife.80271