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A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3

Core histones package chromosomal DNA and regulate genomic transactions, with their nuclear import and deposition involving importin-β proteins and a dedicated repertoire of histone chaperones. Previously, a histone H3-H4 dimer has been isolated bound to importin-4 (Imp4) and the chaperone ASF1, sug...

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Detalles Bibliográficos
Autores principales: Pardal, Alonso Javier, Bowman, Andrew James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560165/
https://www.ncbi.nlm.nih.gov/pubmed/36066346
http://dx.doi.org/10.7554/eLife.81755