Cargando…

A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3

Core histones package chromosomal DNA and regulate genomic transactions, with their nuclear import and deposition involving importin-β proteins and a dedicated repertoire of histone chaperones. Previously, a histone H3-H4 dimer has been isolated bound to importin-4 (Imp4) and the chaperone ASF1, sug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pardal, Alonso Javier, Bowman, Andrew James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560165/ https://www.ncbi.nlm.nih.gov/pubmed/36066346 http://dx.doi.org/10.7554/eLife.81755

Ejemplares similares

Shaping the import system of mitochondria
por: Tokatlidis, Kostas
Publicado: (2018)

The energy savings-oxidative cost trade-off for migratory birds during endurance flight
por: McWilliams, Scott, et al.
Publicado: (2020)

Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision
por: Castiglione, Gianni M, et al.
Publicado: (2018)

A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1
por: Vercoulen, Yvonne, et al.
Publicado: (2017)

SON and SRRM2 are essential for nuclear speckle formation
por: Ilik, İbrahim Avşar, et al.
Publicado: (2020)

Mitochondrial protein import clogging as a mechanism of disease
por: Coyne, Liam P, et al.
Publicado: (2023)

Edge-strand of BepA interacts with immature LptD on the β-barrel assembly machine to direct it to on- and off-pathways
por: Miyazaki, Ryoji, et al.
Publicado: (2021)

Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes
por: von Känel, Corinne, et al.
Publicado: (2020)

Distinct and evolutionary conserved structural features of the human nuclear exosome complex
por: Gerlach, Piotr, et al.
Publicado: (2018)

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
por: Shang, Jinsai, et al.
Publicado: (2018)

Independent evolution of functionally exchangeable mitochondrial outer membrane import complexes
por: Vitali, Daniela G, et al.
Publicado: (2018)

YTHDC1 mediates nuclear export of N(6)-methyladenosine methylated mRNAs
por: Roundtree, Ian A, et al.
Publicado: (2017)

Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
por: Travis, Amanda M, et al.
Publicado: (2023)

Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import
por: Denkert, Niels, et al.
Publicado: (2017)

Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers
por: de Boer, Marijn, et al.
Publicado: (2019)

Extensive cargo identification reveals distinct biological roles of the 12 importin pathways
por: Kimura, Makoto, et al.
Publicado: (2017)

Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals
por: Li, Yuling, et al.
Publicado: (2019)

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology
por: Pawar, Sumit, et al.
Publicado: (2017)

The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP
por: Körner, Maria, et al.
Publicado: (2023)

A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA
por: Winger, Jessica, et al.
Publicado: (2018)

When pH comes to the rescue
por: Gonçalves, Davi, et al.
Publicado: (2020)

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes
por: Ford, Holly C, et al.
Publicado: (2022)

Conformational distributions of isolated myosin motor domains encode their mechanochemical properties
por: Porter, Justin R, et al.
Publicado: (2020)

Immunoproteasome functions explained by divergence in cleavage specificity and regulation
por: Winter, Michael B, et al.
Publicado: (2017)

DnaJC7 specifically regulates tau seeding
por: Perez, Valerie Ann, et al.
Publicado: (2023)

Molecular basis for the adaptive evolution of environment-sensing by H-NS proteins
por: Zhao, Xiaochuan, et al.
Publicado: (2021)

Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function
por: Feng, Suihan, et al.
Publicado: (2018)

SETD3 protein is the actin-specific histidine N-methyltransferase
por: Kwiatkowski, Sebastian, et al.
Publicado: (2018)

Origin and evolution of transporter substrate specificity within the NPF family
por: Jørgensen, Morten Egevang, et al.
Publicado: (2017)

Basis of specificity for a conserved and promiscuous chromatin remodeling protein
por: Donovan, Drake A, et al.
Publicado: (2021)

Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate
por: Rodriguez Camargo, Diana C, et al.
Publicado: (2017)

Correction: Origin and evolution of transporter substrate specificity within the NPF family
por: Jørgensen, Morten Egevang, et al.
Publicado: (2019)

Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
por: Zhu, Xinyu, et al.
Publicado: (2021)

Tissue-specific targeting of DNA nanodevices in a multicellular living organism
por: Chakraborty, Kasturi, et al.
Publicado: (2021)

Protomer alignment modulates specificity of RNA substrate recognition by Ire1
por: Li, Weihan, et al.
Publicado: (2021)

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics
por: Nune, Melesse, et al.
Publicado: (2019)

Divergent Cl(-) and H(+) pathways underlie transport coupling and gating in CLC exchangers and channels
por: Leisle, Lilia, et al.
Publicado: (2020)

Neutrophil-generated HOCl leads to non-specific thiol oxidation in phagocytized bacteria
por: Degrossoli, Adriana, et al.
Publicado: (2018)

Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme
por: Fedoryshchak, Roman O, et al.
Publicado: (2020)

Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library
por: Lite, Thuy-Lan V, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_53huphe40gjdu8mpdl1j50g3ke