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The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration

The visual cycle refers to a series of biochemical reactions of retinoids in ocular tissues and supports the vision in vertebrates. The visual cycle regenerates visual pigments chromophore, 11-cis-retinal, and eliminates its toxic byproducts from the retina, supporting visual function and retinal ne...

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Detalles Bibliográficos
Autores principales: Wang, Yuhong, Ma, Xiang, Muthuraman, Parthasarathy, Raja, Arun, Jayaraman, Aravindan, Petrukhin, Konstantin, Cioffi, Christopher L., Ma, Jian-Xing, Moiseyev, Gennadiy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560169/
https://www.ncbi.nlm.nih.gov/pubmed/36227868
http://dx.doi.org/10.1371/journal.pone.0269437