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The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration
The visual cycle refers to a series of biochemical reactions of retinoids in ocular tissues and supports the vision in vertebrates. The visual cycle regenerates visual pigments chromophore, 11-cis-retinal, and eliminates its toxic byproducts from the retina, supporting visual function and retinal ne...
Autores principales: | Wang, Yuhong, Ma, Xiang, Muthuraman, Parthasarathy, Raja, Arun, Jayaraman, Aravindan, Petrukhin, Konstantin, Cioffi, Christopher L., Ma, Jian-Xing, Moiseyev, Gennadiy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560169/ https://www.ncbi.nlm.nih.gov/pubmed/36227868 http://dx.doi.org/10.1371/journal.pone.0269437 |
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