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The choice of the objective function in flux balance analysis is crucial for predicting replicative lifespans in yeast
Flux balance analysis (FBA) is a powerful tool to study genome-scale models of the cellular metabolism, based on finding the optimal flux distributions over the network. While the objective function is crucial for the outcome, its choice, even though motivated by evolutionary arguments, has not been...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560524/ https://www.ncbi.nlm.nih.gov/pubmed/36227951 http://dx.doi.org/10.1371/journal.pone.0276112 |