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Successful Proof-of-Concept for Topical Delivery of Novel Peptide ALM201 with Potential Usefulness for Treating Neovascular Eye Disorders

PURPOSE: To evaluate the therapeutic benefit of a novel peptide, ALM201, in ocular pathologic vascularization. DESIGN: Experimental study in mouse, rat, and rabbit animal models. PARTICIPANTS: Ten-week-old Lister Hooded male rats, 8-week-old Brown Norway male rats, 9-day-old C57BL/6J mice, and 12-mo...

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Detalles Bibliográficos
Autores principales: Obasanmi, Gideon, Nesbit, M. Andrew, Cobice, Diego, Mackay, Logan, McGimpsey, Stuart, Wappett, Mark, Cranston, Aaron N., Moore, Tara C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560569/
https://www.ncbi.nlm.nih.gov/pubmed/36249680
http://dx.doi.org/10.1016/j.xops.2022.100150