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Variant calling enhances the identification of cancer cells in single-cell RNA sequencing data
Single-cell RNA-sequencing is an invaluable research tool that allows for the investigation of gene expression in heterogeneous cancer cell populations in ways that bulk RNA-seq cannot. However, normal (i.e., non tumor) cells in cancer samples have the potential to confound the downstream analysis o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560611/ https://www.ncbi.nlm.nih.gov/pubmed/36191033 http://dx.doi.org/10.1371/journal.pcbi.1010576 |