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Variant calling enhances the identification of cancer cells in single-cell RNA sequencing data

Single-cell RNA-sequencing is an invaluable research tool that allows for the investigation of gene expression in heterogeneous cancer cell populations in ways that bulk RNA-seq cannot. However, normal (i.e., non tumor) cells in cancer samples have the potential to confound the downstream analysis o...

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Detalles Bibliográficos
Autores principales:	Gasper, William, Rossi, Francesca, Ligorio, Matteo, Ghersi, Dario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560611/ https://www.ncbi.nlm.nih.gov/pubmed/36191033 http://dx.doi.org/10.1371/journal.pcbi.1010576

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