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A phase II multicenter randomized study to evaluate the safety and efficacy of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World

BACKGROUND: Systemic pentavalent antimonials, mainly meglumine antimoniate, continue to be the first-choice drugs for treatment of cutaneous leishmaniasis (CL) despite their toxicity, difficulty of administration and high cost. In the search for therapeutic alternatives, combining two treatment inte...

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Detalles Bibliográficos
Autores principales: López, Liliana, Valencia, Braulio, Alvarez, Fiorela, Ramos, Ana Pilar, Llanos-Cuentas, Alejandro, Echevarria, Juan, Vélez, Iván, Boni, Marina, Rode, Joelle, Quintero, Juliana, Jiménez, Alejandra, Tabares, Yulied, Méndez, Claudia, Arana, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560618/
https://www.ncbi.nlm.nih.gov/pubmed/35255096
http://dx.doi.org/10.1371/journal.pntd.0010238