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Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure

BACKGROUND: Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is a serious public health problem throughout Latin America. With 6 million people infected, there is a major international effort to develop new drugs. In the chronic phase of the disease, the parasite burden is ex...

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Detalles Bibliográficos
Autores principales: Francisco, Amanda Fortes, Saade, Ursula, Jayawardhana, Shiromani, Pottel, Hans, Scandale, Ivan, Chatelain, Eric, Liehl, Peter, Kelly, John M., Zrein, Maan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560623/
https://www.ncbi.nlm.nih.gov/pubmed/36190992
http://dx.doi.org/10.1371/journal.pntd.0010827