Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis

The role of the mucosal pulmonary antibody response in coronavirus disease 2019 (COVID-19) outcome remains unclear. Here, we found that in bronchoalveolar lavage (BAL) samples from 48 patients with severe COVID-19-infected with the ancestral Wuhan virus, mucosal IgG and IgA specific for S1, receptor...

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Detalles Bibliográficos
Autores principales: Ruiz, Maria Julia, Siracusano, Gabriel, Cottignies-Calamarte, Andréa, Tudor, Daniela, Real, Fernando, Zhu, Aiwei, Pastori, Claudia, Capron, Claude, Rosenberg, Arielle R., Temperton, Nigel, Cantoni, Diego, Liao, Hanqing, Ternette, Nicola, Moine, Pierre, Godement, Mathieu, Geri, Guillaume, Chiche, Jean-Daniel, Annane, Djillali, Cramer Bordé, Elisabeth, Lopalco, Lucia, Bomsel, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560774/
https://www.ncbi.nlm.nih.gov/pubmed/36248831
http://dx.doi.org/10.3389/fimmu.2022.842468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560774/
https://www.ncbi.nlm.nih.gov/pubmed/36248831
http://dx.doi.org/10.3389/fimmu.2022.842468

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