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Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis
The role of the mucosal pulmonary antibody response in coronavirus disease 2019 (COVID-19) outcome remains unclear. Here, we found that in bronchoalveolar lavage (BAL) samples from 48 patients with severe COVID-19-infected with the ancestral Wuhan virus, mucosal IgG and IgA specific for S1, receptor...
Autores principales: | Ruiz, Maria Julia, Siracusano, Gabriel, Cottignies-Calamarte, Andréa, Tudor, Daniela, Real, Fernando, Zhu, Aiwei, Pastori, Claudia, Capron, Claude, Rosenberg, Arielle R., Temperton, Nigel, Cantoni, Diego, Liao, Hanqing, Ternette, Nicola, Moine, Pierre, Godement, Mathieu, Geri, Guillaume, Chiche, Jean-Daniel, Annane, Djillali, Cramer Bordé, Elisabeth, Lopalco, Lucia, Bomsel, Morgane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560774/ https://www.ncbi.nlm.nih.gov/pubmed/36248831 http://dx.doi.org/10.3389/fimmu.2022.842468 |
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