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Membrane Bound CRT Fragment Accelerates Tumor Growth of Melanoma B16 Cell In Vivo through Promoting M2 Polarization via TLR4

Calreticulin (CRT) is a major calcium-binding luminal resident protein on the endoplasmic reticulum that can also be released extracellular as well as anchored on surface of cells. Previously, we demonstrated that soluble recombinant CRT fragment 39-272 (CRT/39-272) exhibited potent immunostimulator...

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Detalles Bibliográficos
Autores principales: Wang, Hong-Min, Zhou, Zhe, Miao, Jie, Zhu, Bo, Dai, Xiao-Qiu, Zhong, Qiao, Gong, Fang-Yuan, Gao, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560857/
https://www.ncbi.nlm.nih.gov/pubmed/36249426
http://dx.doi.org/10.1155/2022/4626813