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Exercise regulates shelterin genes and microRNAs implicated in ageing in Thoroughbred horses
Ageing causes a gradual deterioration of bodily functions and telomere degradation. Excessive telomere shortening leads to cellular senescence and decreases tissue vitality. Six proteins, called shelterin, protect telomere integrity and control telomere length through telomerase-dependent mechanisms...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560944/ https://www.ncbi.nlm.nih.gov/pubmed/36085194 http://dx.doi.org/10.1007/s00424-022-02745-0 |