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Exercise regulates shelterin genes and microRNAs implicated in ageing in Thoroughbred horses

Ageing causes a gradual deterioration of bodily functions and telomere degradation. Excessive telomere shortening leads to cellular senescence and decreases tissue vitality. Six proteins, called shelterin, protect telomere integrity and control telomere length through telomerase-dependent mechanisms...

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Detalles Bibliográficos
Autores principales: Mandal, Shama, Denham, Michele M., Spencer, Sarah J., Denham, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560944/
https://www.ncbi.nlm.nih.gov/pubmed/36085194
http://dx.doi.org/10.1007/s00424-022-02745-0