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Multi‐state modeling of G‐protein coupled receptors at experimental accuracy

The family of G‐protein coupled receptors (GPCRs) is one of the largest protein families in the human genome. GPCRs transduct chemical signals from extracellular to intracellular regions via a conformational switch between active and inactive states upon ligand binding. While experimental structures...

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Detalles Bibliográficos
Autores principales: Heo, Lim, Feig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561049/
https://www.ncbi.nlm.nih.gov/pubmed/35510704
http://dx.doi.org/10.1002/prot.26382