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Multi‐state modeling of G‐protein coupled receptors at experimental accuracy
The family of G‐protein coupled receptors (GPCRs) is one of the largest protein families in the human genome. GPCRs transduct chemical signals from extracellular to intracellular regions via a conformational switch between active and inactive states upon ligand binding. While experimental structures...
Autores principales: | Heo, Lim, Feig, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561049/ https://www.ncbi.nlm.nih.gov/pubmed/35510704 http://dx.doi.org/10.1002/prot.26382 |
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