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Carrier-free supramolecular nanoassemblies of pure LSD1 inhibitor for effective anti-tumor therapy

The LSD1 protein is an oxidase that regulates protein methylation, which regulates gene expression and triggers tumors. Previously, inhibiting LSD1 has been found to be an effective treatment strategy for opposing tumors caused by overexpression of LSD1. Our recent study found that compound 17i was...

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Detalles Bibliográficos
Autores principales: Li, Boao, Zhang, Xiangyu, Li, Jibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561089/
https://www.ncbi.nlm.nih.gov/pubmed/36247676
http://dx.doi.org/10.3389/fchem.2022.1012882