Cargando…
Carrier-free supramolecular nanoassemblies of pure LSD1 inhibitor for effective anti-tumor therapy
The LSD1 protein is an oxidase that regulates protein methylation, which regulates gene expression and triggers tumors. Previously, inhibiting LSD1 has been found to be an effective treatment strategy for opposing tumors caused by overexpression of LSD1. Our recent study found that compound 17i was...
Autores principales: | Li, Boao, Zhang, Xiangyu, Li, Jibin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561089/ https://www.ncbi.nlm.nih.gov/pubmed/36247676 http://dx.doi.org/10.3389/fchem.2022.1012882 |
Ejemplares similares
-
Programmed supramolecular nanoassemblies: enhanced serum stability and cell specific triggered release of anti-cancer drugs
por: Mondal, Sanchaita, et al.
Publicado: (2019) -
Molecularly engineered carrier-free co-delivery nanoassembly for self-sensitized photothermal cancer therapy
por: Shan, Xinzhu, et al.
Publicado: (2021) -
Welcoming natural isotopic abundance in solid-state NMR: probing π-stacking and supramolecular structure of organic nanoassemblies using DNP
por: Märker, Katharina, et al.
Publicado: (2017) -
Size and charge dual-transformable mesoporous nanoassemblies for enhanced drug delivery and tumor penetration
por: Chen, Liang, et al.
Publicado: (2020) -
Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification
por: Zhao, Yan, et al.
Publicado: (2023)