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Diverse selection pressures shaping the genetic architecture of behçet disease susceptibility

Behçet disease (BD) is a polygenic, multifactorial, multisystem inflammatory condition with unknown etiology. Global distribution of BD is geographically structured, highest prevalence observed among East Asian, Middle Eastern, and Mediterranean populations. Although adaptive selection on a few BD s...

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Detalles Bibliográficos
Autores principales: Sezgin, Efe, Kaplan, Elif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561091/
https://www.ncbi.nlm.nih.gov/pubmed/36246630
http://dx.doi.org/10.3389/fgene.2022.983646