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Olanzapine induces weight gain in offspring of prenatally exposed poly I:C rats by reducing brown fat thermogenic activity

Background: Olanzapine (OLZ) is an antipsychotic with a high risk of metabolic syndrome, and its induced metabolic disturbance may be related to the thermogenic function of brown adipose tissue (BAT). Of note is that schizophrenia itself appears to be associated with a higher incidence of metabolic...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoying, Liu, Lu, Zeng, Yanping, Li, Dejuan, Liu, Xuemei, Hu, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561095/
https://www.ncbi.nlm.nih.gov/pubmed/36249777
http://dx.doi.org/10.3389/fphar.2022.1001919