Halogen Atom Participation in Guiding the Stereochemical Outcomes of Acetal Substitution Reactions

Acetal substitution reactions of α‐halogenated five‐ and six‐membered rings can be highly stereoselective. Erosion of stereoselectivity occurs as nucleophilicity increases, which is consistent with additions to a halogen‐stabilized oxocarbenium ion, not a three‐membered‐ring halonium ion. Computatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Demkiw, Krystyna M., Remmerswaal, Wouter A., Hansen, Thomas, van der Marel, Gijsbert A., Codée, Jeroen D. C., Woerpel, K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561118/
https://www.ncbi.nlm.nih.gov/pubmed/35980341
http://dx.doi.org/10.1002/anie.202209401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561118/
https://www.ncbi.nlm.nih.gov/pubmed/35980341
http://dx.doi.org/10.1002/anie.202209401

Ejemplares similares