Aminooxyacetic acid hemihydrochloride inhibits osteoclast differentiation and bone resorption by attenuating oxidative phosphorylation

Osteoclasts undergo active metabolic reprogramming to acquire the energy needed during differentiation and bone resorption. Compared with immature osteoclasts, mature osteoclasts comprise higher levels of electron transport chain enzymes and more metabolically active mitochondria. Of all energy meta...

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Detalles Bibliográficos
Autores principales: Yang, Biao, Su, Yuangang, Han, Shuai, Chen, Runfeng, Sun, Ran, Rong, Kewei, Long, Feng, Teng, Hailong, Zhao, Jinmin, Liu, Qian, Qin, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561130/
https://www.ncbi.nlm.nih.gov/pubmed/36249744
http://dx.doi.org/10.3389/fphar.2022.980678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561130/
https://www.ncbi.nlm.nih.gov/pubmed/36249744
http://dx.doi.org/10.3389/fphar.2022.980678

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