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Structural studies of the phosphoribosyltransferase involved in cobamide biosynthesis in methanogenic archaea and cyanobacteria

Cobamides (Cbas) are coenzymes used by cells across all domains of life, but de novo synthesis is only found in some bacteria and archaea. Five enzymes assemble the nucleotide loop in the alpha phase of the corrin ring. Condensation of the activated ring and nucleobase yields adenosyl-Cba 5′-phospha...

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Detalles Bibliográficos
Autores principales: Jeter, Victoria L., Schwarzwalder, Anne H., Rayment, Ivan, Escalante-Semerena, Jorge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561151/
https://www.ncbi.nlm.nih.gov/pubmed/36229494
http://dx.doi.org/10.1038/s41598-022-21765-5