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Reno-protective effect of mangiferin against methotrexate-induced kidney damage in male rats: PPARγ-mediated antioxidant activity

Methotrexate (MTX) is an immunosuppressant used for the treatment of cancer and autoimmune diseases. MTX has a major adverse effect, acute kidney injury, which limits its use. Mangiferin (MF) is a natural bioactive xanthonoid used as a traditional herbal supplement to boost the immune system due to...

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Detalles Bibliográficos
Autores principales: Attia, Seba Hassan, Elshazly, Shimaa Mustafa, Abdelaal, Mahmoud Mohamed, Soliman, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561181/
https://www.ncbi.nlm.nih.gov/pubmed/36249937
http://dx.doi.org/10.1016/j.jsps.2022.06.026