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Reno-protective effect of mangiferin against methotrexate-induced kidney damage in male rats: PPARγ-mediated antioxidant activity
Methotrexate (MTX) is an immunosuppressant used for the treatment of cancer and autoimmune diseases. MTX has a major adverse effect, acute kidney injury, which limits its use. Mangiferin (MF) is a natural bioactive xanthonoid used as a traditional herbal supplement to boost the immune system due to...
Autores principales: | Attia, Seba Hassan, Elshazly, Shimaa Mustafa, Abdelaal, Mahmoud Mohamed, Soliman, Eman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561181/ https://www.ncbi.nlm.nih.gov/pubmed/36249937 http://dx.doi.org/10.1016/j.jsps.2022.06.026 |
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