Super-enhancer-controlled positive feedback loop BRD4/ERα–RET–ERα promotes ERα-positive breast cancer

Estrogen and estrogen receptor alpha (ERα)-induced gene transcription is tightly associated with ERα-positive breast carcinogenesis. ERα-occupied enhancers, particularly super-enhancers, have been suggested to play a vital role in regulating such transcriptional events. However, the landscape of ERα...

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Detalles Bibliográficos
Autores principales: Zheng, Zao-zao, Xia, Lin, Hu, Guo-sheng, Liu, Jun-yi, Hu, Ya-hong, Chen, Yu-jie, Peng, Jia-yin, Zhang, Wen-juan, Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561272/
https://www.ncbi.nlm.nih.gov/pubmed/36124682
http://dx.doi.org/10.1093/nar/gkac778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561272/
https://www.ncbi.nlm.nih.gov/pubmed/36124682
http://dx.doi.org/10.1093/nar/gkac778

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