Cargando…
SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination
Human CtIP maintains genomic integrity primarily by promoting 5′ DNA end resection, an initial step of the homologous recombination (HR). A few mechanisms have been suggested as to how CtIP recruitment to damage sites is controlled, but it is likely that we do not yet have full understanding of the...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561274/ https://www.ncbi.nlm.nih.gov/pubmed/36155803 http://dx.doi.org/10.1093/nar/gkac808 |