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Identification of tumor-specific neoantigens and immune clusters of hepatocellular carcinoma for mRNA vaccine development
BACKGROUND: To screen efficacious neoantigens for the development of LIHC mRNA vaccines, construct LIHC immune clusters, and therefore select patients who might benefit from vaccination. METHODS: RNA-seq data and clinical information of 371 TCGA-LIHC and 231 ICGC-LIHC cohorts were downloaded. Differ...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561321/ https://www.ncbi.nlm.nih.gov/pubmed/36239794 http://dx.doi.org/10.1007/s00432-022-04285-7 |