Identification of tumor-specific neoantigens and immune clusters of hepatocellular carcinoma for mRNA vaccine development

BACKGROUND: To screen efficacious neoantigens for the development of LIHC mRNA vaccines, construct LIHC immune clusters, and therefore select patients who might benefit from vaccination. METHODS: RNA-seq data and clinical information of 371 TCGA-LIHC and 231 ICGC-LIHC cohorts were downloaded. Differ...

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Detalles Bibliográficos
Autores principales: Li, Yi-Fei, Hou, Qiong-Qiong, Zhao, Shuang, Chen, Xiaoyan, Tang, Min, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561321/
https://www.ncbi.nlm.nih.gov/pubmed/36239794
http://dx.doi.org/10.1007/s00432-022-04285-7

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