Targeted de novo phasing and long-range assembly by template mutagenesis

Short-read sequencers provide highly accurate reads at very low cost. Unfortunately, short reads are often inadequate for important applications such as assembly in complex regions or phasing across distant heterozygous sites. In this study, we describe novel bench protocols and algorithms to obtain...

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Detalles Bibliográficos
Autores principales: Li, Siran, Park, Sarah, Ye, Catherine, Danyko, Cassidy, Wroten, Matthew, Andrews, Peter, Wigler, Michael, Levy, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561374/
https://www.ncbi.nlm.nih.gov/pubmed/35822882
http://dx.doi.org/10.1093/nar/gkac592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561374/
https://www.ncbi.nlm.nih.gov/pubmed/35822882
http://dx.doi.org/10.1093/nar/gkac592

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