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Genetic context effects can override canonical cis regulatory elements in Escherichia coli

Recent experiments have shown that in addition to control by cis regulatory elements, the local chromosomal context of a gene also has a profound impact on its transcription. Although this chromosome-position dependent expression variation has been empirically mapped at high-resolution, the underlyi...

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Detalles Bibliográficos
Autores principales: Scholz, Scott A, Lindeboom, Chase D, Freddolino, Peter L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561378/
https://www.ncbi.nlm.nih.gov/pubmed/36134716
http://dx.doi.org/10.1093/nar/gkac787