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A massively parallel reporter assay reveals focused and broadly encoded RNA localization signals in neurons

Asymmetric subcellular mRNA localization allows spatial regulation of gene expression and functional compartmentalization. In neurons, localization of specific mRNAs to neurites is essential for cellular functioning. However, it is largely unknown how transcript sorting works in a sequence-specific...

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Detalles Bibliográficos
Autores principales: Mikl, Martin, Eletto, Davide, Nijim, Malak, Lee, Minkyoung, Lafzi, Atefeh, Mhamedi, Farah, David, Orit, Sain, Simona Baghai, Handler, Kristina, Moor, Andreas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561380/
https://www.ncbi.nlm.nih.gov/pubmed/36156153
http://dx.doi.org/10.1093/nar/gkac806