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Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells

Atherosclerosis is a chronic inflammatory disease and occurs preferentially in arterial regions exposed to disturbed blood flow (d-flow) while the stable flow (s-flow) regions are spared. D-flow induces endothelial inflammation and atherosclerosis by regulating endothelial gene expression partly thr...

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Detalles Bibliográficos
Autores principales: Demos, Catherine, Johnson, Janie, Andueza, Aitor, Park, Christian, Kim, Yerin, Villa-Roel, Nicolas, Kang, Dong-Won, Kumar, Sandeep, Jo, Hanjoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561411/
https://www.ncbi.nlm.nih.gov/pubmed/36247423
http://dx.doi.org/10.3389/fcvm.2022.979745