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A new obligate CXCL4–CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms

Chemokines form a family of proteins with critical roles in many biological processes in health and disease conditions, including cardiovascular, autoimmune diseases, infections, and cancer. Many chemokines engage in heterophilic interactions to form heterodimers, leading to synergistic activity enh...

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Detalles Bibliográficos
Autores principales: Nguyen, Khanh T.P., Volkman, Brian, Dréau, Didier, Nesmelova, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561612/
https://www.ncbi.nlm.nih.gov/pubmed/36229490
http://dx.doi.org/10.1038/s41598-022-21651-0