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Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells

In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO, to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022).

Detalles Bibliográficos
Autores principales: Tang, Qingyuan, Schweitzer, Jeffrey S., Song, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561634/
https://www.ncbi.nlm.nih.gov/pubmed/36179693
http://dx.doi.org/10.1016/j.stemcr.2022.09.002