Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells

In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO, to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022).

Detalles Bibliográficos
Autores principales: Tang, Qingyuan, Schweitzer, Jeffrey S., Song, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561634/
https://www.ncbi.nlm.nih.gov/pubmed/36179693
http://dx.doi.org/10.1016/j.stemcr.2022.09.002
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author Tang, Qingyuan
Schweitzer, Jeffrey S.
Song, Bin
author_facet Tang, Qingyuan
Schweitzer, Jeffrey S.
Song, Bin
author_sort Tang, Qingyuan
collection PubMed
description In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO, to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022).
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spelling pubmed-95616342022-10-15 Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells Tang, Qingyuan Schweitzer, Jeffrey S. Song, Bin Stem Cell Reports Commentary In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO, to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022). Elsevier 2022-09-29 /pmc/articles/PMC9561634/ /pubmed/36179693 http://dx.doi.org/10.1016/j.stemcr.2022.09.002 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Commentary
Tang, Qingyuan
Schweitzer, Jeffrey S.
Song, Bin
Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title_full Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title_fullStr Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title_full_unstemmed Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title_short Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
title_sort panning for gold: purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561634/
https://www.ncbi.nlm.nih.gov/pubmed/36179693
http://dx.doi.org/10.1016/j.stemcr.2022.09.002
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AT schweitzerjeffreys panningforgoldpurifyingmesencephalicdopaminergicprogenitorsdifferentiatedfromhumanpluripotentstemcells
AT songbin panningforgoldpurifyingmesencephalicdopaminergicprogenitorsdifferentiatedfromhumanpluripotentstemcells

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