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Lung mitochondrial DNA copy number, inflammatory biomarkers, gene transcription and gene methylation in vapers and smokers

BACKGROUND: Mitochondrial DNA copy number (mtCN) maintains cellular function and homeostasis, and is linked to nuclear DNA methylation and gene expression. Increased mtCN in the blood is associated with smoking and respiratory disease, but has received little attention for target organ effects for s...

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Detalles Bibliográficos
Autores principales: Mori, Kellie M., McElroy, Joseph P., Weng, Daniel Y., Chung, Sangwoon, Fadda, Paolo, Reisinger, Sarah A., Ying, Kevin L., Brasky, Theodore M., Wewers, Mark D., Freudenheim, Jo L., Shields, Peter G., Song, Min-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561685/
https://www.ncbi.nlm.nih.gov/pubmed/36215783
http://dx.doi.org/10.1016/j.ebiom.2022.104301