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Lung mitochondrial DNA copy number, inflammatory biomarkers, gene transcription and gene methylation in vapers and smokers
BACKGROUND: Mitochondrial DNA copy number (mtCN) maintains cellular function and homeostasis, and is linked to nuclear DNA methylation and gene expression. Increased mtCN in the blood is associated with smoking and respiratory disease, but has received little attention for target organ effects for s...
Autores principales: | Mori, Kellie M., McElroy, Joseph P., Weng, Daniel Y., Chung, Sangwoon, Fadda, Paolo, Reisinger, Sarah A., Ying, Kevin L., Brasky, Theodore M., Wewers, Mark D., Freudenheim, Jo L., Shields, Peter G., Song, Min-Ae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561685/ https://www.ncbi.nlm.nih.gov/pubmed/36215783 http://dx.doi.org/10.1016/j.ebiom.2022.104301 |
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