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Integrated metagenomics and targeted-metabolomics analysis of the effects of phenylalanine on loperamide-induced constipation in rats

Functional constipation is a common functional gastrointestinal disease. In our previous study, we found that the gut microbiota structure was disordered and the level of phenylalanine (Phe) in serum was decreased in constipated women. We conducted the present study to elucidate the role of Phe in r...

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Detalles Bibliográficos
Autores principales: Yang, Chuanli, Bai, Xinshu, Hu, Tianjiao, Xue, Xin, Su, Xiaohu, Zhang, Xuan, Wu, Teng, Zhang, Mingxia, Shen, Xiaobing, Dong, Xiushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561758/
https://www.ncbi.nlm.nih.gov/pubmed/36246281
http://dx.doi.org/10.3389/fmicb.2022.1018008