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Semi-rational engineering membrane binding domain of L-amino acid deaminase from Proteus vulgaris for enhanced α-ketoisocaproate

α-Keto acids are important raw materials for pharmaceuticals and functional foods, which could be produced from cheap feed stock by whole cell biocatalysts containing L-amino acid deaminases (L-AADs). However, the production capacity is limited by the low activity of L-AADs. The L-AAD mediated redox...

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Detalles Bibliográficos
Autores principales: Song, Yang, Wang, Rui, Zhang, Zixuan, Liu, Xinran, Qi, Lulu, Shentu, Xuping, Yu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561763/
https://www.ncbi.nlm.nih.gov/pubmed/36246292
http://dx.doi.org/10.3389/fmicb.2022.1025845