New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis

Excess iron accumulation occurs in organs of patients with certain genetic disorders or after repeated transfusions. No physiological mechanism is available to excrete excess iron and iron overload to promote lipid peroxidation to induce ferroptosis, thus iron chelation becomes critical for preventi...

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Detalles Bibliográficos
Autores principales: Feng, Wenya, Xiao, Yuanjing, Zhao, Chuanfang, Zhang, Zhanming, Liu, Wei, Ma, Juan, Ganz, Tomas, Zhang, Junliang, Liu, Sijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561787/
https://www.ncbi.nlm.nih.gov/pubmed/36031399
http://dx.doi.org/10.1002/advs.202202679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561787/
https://www.ncbi.nlm.nih.gov/pubmed/36031399
http://dx.doi.org/10.1002/advs.202202679

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