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TAK1 is essential for endothelial barrier maintenance and repair after lung vascular injury

TGF–β-activated kinase 1 (TAK1) plays crucial roles in innate and adaptive immune responses and is required for embryonic vascular development. However, TAK1’s role in regulating vascular barrier integrity is not well defined. Here we show that endothelial TAK1 kinase function is required to maintai...

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Detalles Bibliográficos
Autores principales: Wang, Dong-Mei, Soni, Dheeraj, Regmi, Sushil C., Vogel, Stephen M., Tiruppathi, Chinnaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561857/
https://www.ncbi.nlm.nih.gov/pubmed/35324316
http://dx.doi.org/10.1091/mbc.E21-11-0563