Versatile Nano‐PROTAC‐Induced Epigenetic Reader Degradation for Efficient Lung Cancer Therapy

Recent evidence has indicated that overexpression of the epigenetic reader bromodomain‐containing protein 4 (BRD4) contributes to a poor prognosis of lung cancers, and the suppression of its expression promotes cell apoptosis and leads to tumor shrinkage. Proteolysis targeting chimera (PROTAC) has r...

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Detalles Bibliográficos
Autores principales: Zhang, Huan‐Tian, Peng, Rui, Chen, Sheng, Shen, Ao, Zhao, Lixin, Tang, Wang, Wang, Xiao‐He, Li, Zhen‐Yan, Zha, Zhen‐Gang, Yi, Mengmeng, Zhang, Lingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561860/
https://www.ncbi.nlm.nih.gov/pubmed/35988145
http://dx.doi.org/10.1002/advs.202202039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561860/
https://www.ncbi.nlm.nih.gov/pubmed/35988145
http://dx.doi.org/10.1002/advs.202202039

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