Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer

SIMPLE SUMMARY: In this study, we generate an innovative endogenous progesterone receptor (PR) reporter gene containing endometrial cancer cell lines and use this tool to visualize PR expression in real-time. We also demonstrated two strategies of using this reporter gene: (1). Drug discovery—screen...

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Detalles Bibliográficos
Autores principales: Li, Yiyang, Zhou, Wei, Meng, Xiangbing, Murray, Sarina D., Li, Long, Fronk, Abby, Lazaro-Camp, Vanessa J., Wen, Kuo-kuang, Wu, Meng, Dupuy, Adam, Leslie, Kimberly K., Yang, Shujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561963/
https://www.ncbi.nlm.nih.gov/pubmed/36230806
http://dx.doi.org/10.3390/cancers14194883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561963/
https://www.ncbi.nlm.nih.gov/pubmed/36230806
http://dx.doi.org/10.3390/cancers14194883

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